Monomeric E6AP-E6-p53 ternary complex
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8r1f
Q-score: 0.316
Sandate CR, Chakraborty D, Kater L, Kempf G, Thomae NH
To Be Published
- Ubiquitin-like protein smt3,protein e6 (31 kDa, Protein from Human papillomavirus type 16)
- Zinc ion (65 Da, Ligand)
- Cellular tumor antigen p53 (46 kDa, Protein from Homo sapiens)
- Ubiquitin-protein ligase e3a (103 kDa, Protein from Homo sapiens)
- Monomeric e6ap-e6-p53 ternary complex (176 kDa, Complex from Homo sapiens)
Dimeric ternary structure of E6AP-E6-p53
Resolution: 3.99 Å
EM Method: Single-particle
Fitted PDBs: 8r1g
Q-score: 0.175
Sandate CR, Chakraborty D, Kater L, Kempf G, Thomae NH
To Be Published
- Ubiquitin-like protein smt3,protein e6 (31 kDa, Protein from Human papillomavirus type 16)
- Zinc ion (65 Da, Ligand)
- Dimeric e6ap-e6-p53 ternary complex (352 kDa, Complex from Homo sapiens)
- Cellular tumor antigen p53 (46 kDa, Protein from Homo sapiens)
- Ubiquitin-protein ligase e3a (103 kDa, Protein from Homo sapiens)
Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP
Resolution: 4.24 Å
EM Method: Single-particle
Fitted PDBs: 8pjj
Q-score: 0.218
To Be Published
- Dosage compensation regulator (Complex from Drosophila melanogaster)
- Complex of mle, sl7uuc and adp (150 kDa, Complex)
- Sl7uuc rna (19 kDa, RNA from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Sl7uuc rna (Complex from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with UUC RNA and ADP
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8pjb
Q-score: 0.415
To Be Published
- Complex of mle, uuc and adp (134 kDa, Complex)
- Magnesium ion (24 Da, Ligand)
- Dosage compensation regulator (Complex from Drosophila melanogaster)
- Rna (5'-r(p*cp*up*cp*up*up*up*cp*up*u)-3') (Complex from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Rna (5'-r(p*cp*up*cp*up*up*up*cp*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8b9g
Q-score: 0.513
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Water (18 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Mle in complex with adp:alf4 and u10 rna (133 kDa, Complex from Drosophila melanogaster)
- Rna (5'-r(p*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8b9i
Q-score: 0.469
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Rna (5'-r(p*cp*cp*up*cp*up*up*up*cp*up*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Mle in complex with adp:alf4 and uuc rna (133 kDa, Complex from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with ADP:AlF4
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8b9j
Q-score: 0.416
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Mle in complex with adp:alf4 (130 kDa, Cellular component from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 8b9k
Q-score: 0.239
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Mle in complex with adp:alf4 and sl7moduuc rna (149 kDa, Complex from Drosophila melanogaster)
- Sl7moduuc (19 kDa, RNA from Drosophila melanogaster)
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8b9l
Q-score: 0.345
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Mle (130 kDa, Cellular component from Drosophila melanogaster)
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8svf
Q-score: 0.383
Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ
Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ Pubmed: 37556531 DOI: doi:10.1126/sciadv.adg9832 ]
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Ubiquitin carboxyl-terminal hydrolase bap1 (80 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Bap1/asxl1 bound to the h2ak119ub nucleosome (Complex from Homo sapiens)
- Dna/rna (327-mer) (102 kDa, Macromolecule from synthetic construct)
- Polycomb group protein asxl1 (165 kDa, Protein from Homo sapiens)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Dna/rna (187-mer) (58 kDa, Macromolecule from synthetic construct)